Handling biological sequence alignments on networked computing systems: A divide-and-conquer approach

In this paper, we address the biological sequence alignment problem, which is one of the most commonly used steps in several bioinformatics applications. We employ the Divisible Load Theory (DLT) paradigm that is suitable for handling large-scale processing on network-based systems to achieve a high...

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Veröffentlicht in:	Journal of parallel and distributed computing 2009-10, Vol.69 (10), p.854-865
Hauptverfasser:	Bharadwaj, Veeravalli, Wong, Han Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Applied sciences Biological and medical sciences Biological sequences Communication delay Computer science control theory systems Data processing. List processing. Character string processing Divisible load theory Exact sciences and technology Fundamental and applied biological sciences. Psychology Gene expression General aspects General aspects, investigation methods Linear networks Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Memory organisation. Data processing Molecular and cellular biology Molecular genetics Proteins Sequence alignment Smith–Waterman algorithm Software
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