A novel method to evaluate protein solubility using a high throughput screening approach

Protein solubility is a key parameter affecting the performance of every biotechnological downstream processing operation. Current methods used to determine protein solubility data, however, are often characterized by the need of pure protein crystals and long experimental time frames lying in the r...

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Veröffentlicht in:	Chemical engineering science 2009-09, Vol.64 (17), p.3778-3788
Hauptverfasser:	Wiendahl, Matthias, Völker, Christiane, Husemann, Ilka, Krarup, Janus, Staby, Arne, Scholl, Stephan, Hubbuch, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Chemical engineering Evaporation Exact sciences and technology High throughput screening Insulin Precipitation Process development Protein solubility
Online-Zugang:	Volltext
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