Human Platelet Extracts Stimulate the Terminative Differentiation of Growth-Plate Chondrocytes in Rabbit

Human Platelet Extracts Stimulate the Terminative Differentiation of Growth-Plate Chondrocytes in Rabbit

Objective：To observe the effect of human platelet extracts on proliferation and differentiation of rabbit growth-plate chondrocytes in monolayer and fabrication of tissue engineering cartilage in vitro. Method: To determine the effects of platelet extracts at different concentrations on proliferatio...

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Veröffentlicht in:Materials science forum 2009-01, Vol.610-613, p.1070-1075
Hauptverfasser: Tang, Ming Qiao, Yu, Li, Yan, Wei Qun
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Yan, Wei Qun
description Objective：To observe the effect of human platelet extracts on proliferation and differentiation of rabbit growth-plate chondrocytes in monolayer and fabrication of tissue engineering cartilage in vitro. Method: To determine the effects of platelet extracts at different concentrations on proliferation and differentiation of rabbit growth-plate chondrocytes using 3H-TdR、PNP and HE staining. Results: Platelet extracts had very strong stimulative effects on proliferation and differentiation of chondrocytes, especially the hypertropization (termination) of chondrocytes.
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