Human Embryoid Bodies Containing Nano- and Microparticulate Delivery Vehicles

Human Embryoid Bodies Containing Nano- and Microparticulate Delivery Vehicles

Differentiation of human embryonic stem cells is affected by the incorporation of growth‐factor‐releasing particles in embryoid bodies. Incorporation of these particles has a minimal effect on cell viability and proliferation but a large impact on differentiation. The figure shows the distribution o...

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Veröffentlicht in:Advanced materials (Weinheim) 2008-06, Vol.20 (12), p.2285-2291
Hauptverfasser: Ferreira, Lino, Squier, Trevor, Park, Hyoungshin, Choe, Hannah, Kohane, Daniel S., Langer, Robert
Format: Artikel
Sprache:eng
Schlagworte:
bionanotechnology
intracellular trafficking
microparticles
nanoparticles
stem cells
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Zusammenfassung:Differentiation of human embryonic stem cells is affected by the incorporation of growth‐factor‐releasing particles in embryoid bodies. Incorporation of these particles has a minimal effect on cell viability and proliferation but a large impact on differentiation. The figure shows the distribution of TRITC‐labeled microparticles in embryoid bodies, as evaluated by confocal microscopy.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200702404