Microdialysis for pharmacokinetic analysis of drug transport to the brain

The intracerebral microdialysis technique represents an important tool for monitoring free drug concentrations in brain extracellular fluid (brain EcF) as a function of time. With knowledge of associated free plasma concentrations, it provides information on blood–brain barrier (BBB) drug transport....

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Advanced drug delivery reviews 1999-04, Vol.36 (2), p.211-227
Hauptverfasser:	de Lange, Elizabeth C.M., de Boer, Bert A.G., Breimer, Douwe D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Blood–brain barrier Brain Brain extracellular fluid Dialysis Microdialysis Neurophysiology Pharmacokinetics Proteins Surgery
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!