fdrMotif: identifying cis-elements by an EM algorithm coupled with false discovery rate control

Motivation: Most de novo motif identification methods optimize the motif model first and then separately test the statistical significance of the motif score. In the first stage, a motif abundance parameter needs to be specified or modeled. In the second stage, a Z-score or P-value is used as the te...

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Veröffentlicht in:	Bioinformatics 2008-03, Vol.24 (5), p.629-636
Hauptverfasser:	Li, Leping, Bass, Robert L., Liang, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Amino Acid Motifs Binding Sites Biological and medical sciences Fundamental and applied biological sciences. Psychology General aspects Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Models, Theoretical
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