Synthetic bioabsorbable microtubes for the treatment of surgical sites

Bioabsorbable polyglycolide-co-lactide microtubes have been developed for the continuous delivery of fluid medications directly to an operative site. Studies conducted with radio-opaque solution using porcine models indicated that infusion of fluids in the wound site was rapid and complete. The tiss...

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Veröffentlicht in:Materials Science & Engineering C 2008-04, Vol.28 (3), p.331-335
Hauptverfasser: Cichocki, Frank R., Chen, Gavin, Zhou, Jack, Deng, Meng
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container_title Materials Science & Engineering C
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creator Cichocki, Frank R.
Chen, Gavin
Zhou, Jack
Deng, Meng
description Bioabsorbable polyglycolide-co-lactide microtubes have been developed for the continuous delivery of fluid medications directly to an operative site. Studies conducted with radio-opaque solution using porcine models indicated that infusion of fluids in the wound site was rapid and complete. The tissue reaction to the microtube was generally characterized as minimal to mild with complete absorption occurring within 56 days postimplantation. Processing–microstructure-property relationships and bio-degradation characteristics of the microtubes are presented.
doi_str_mv 10.1016/j.msec.2007.04.002
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subjects Bioabsorption
Drug delivery
Microtube
Polyglycolic acid
Polylactic acid
title Synthetic bioabsorbable microtubes for the treatment of surgical sites
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