Investigation into the Potential Mechanism of Radix Paeoniae Rubra Against Ischemic Stroke Based on Network Pharmacology

Radix Paeoniae Rubra (RPR), an edible and medicinal Traditional Chinese Medicine (TCM), is extensively employed in therapeutic interventions of cardiovascular and cerebrovascular diseases. However, the curative effect of RPR on ischemic stroke remains ambiguous. This work integrated network pharmaco...

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Veröffentlicht in:	Nutrients 2024-12, Vol.16 (24), p.4409
Hauptverfasser:	Wen, Tingyu, Xin, Guang, Zhou, Qilong, Wang, Tao, Yu, Xiuxian, Li, Yanceng, Li, Shiyi, Zhang, Ying, Zhang, Kun, Liu, Ting, Zhu, Beiwei, Huang, Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biotechnology Blood clots Blood Platelets - drug effects Blood Platelets - metabolism Bridged-Ring Compounds Chinese medicine Chromatography Disease Disease Models, Animal Drugs, Chinese Herbal - pharmacology Ischemia Ischemic Stroke - drug therapy Laboratory animals Male MAP Kinase Signaling System - drug effects Medical research Mice Mice, Inbred C57BL Molecular Docking Simulation Network Pharmacology Neuroprotective Agents - pharmacology Paeonia - chemistry Pharmacology Proteins Sitosterols - pharmacology
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