Whole-genome sequencing of cell-free DNA reveals DNA of tumor origin in plasma from patients with colorectal adenomas

The presence of circulating tumor DNA (ctDNA) in patients with colorectal adenomas remains uncertain. Studies using tumor-agnostic approaches report ctDNA in 10-15% of patients, though with uncertainty as to whether the signal originates from the adenoma. To obtain an accurate estimate of the propor...

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Veröffentlicht in:Molecular oncology 2025-01
Hauptverfasser: Frydendahl, Amanda, Widman, Adam J, Øgaard, Nadia, Arora, Anushri, Halmos, Daniel, Nors, Jesper, Ahrenfeldt, Johanne, Henriksen, Tenna V, Demuth, Christina, Raaby, Line, Rasmussen, Mads H, Therkildsen, Christina, Landau, Dan A, Andersen, Claus L
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Sprache:eng
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