Progranulin measurement with a new automated method: a step forward in the diagnostic approach to neurodegenerative disorders

Mutations in the gene encoded glycoprotein progranulin (PGRN), cause 5-10 % of all cases of frontotemporal lobar degeneration (FTLD). The aim of our study was to verify the analytical and clinical performance of an automated chemiluminescent immunoassay method for PGRN measurement recently developed...

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Veröffentlicht in:Clinical chemistry and laboratory medicine 2025-01
Hauptverfasser: Cosma, Chiara, Talli, Ilaria, Pangrazzi, Elisa, Padoan, Andrea, Cerutti, Helena, Zaninotto, Martina, Gabelli, Carlo, Plebani, Mario
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Sprache:eng
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