Engineered enzymes for enantioselective nucleophilic aromatic substitutions

Nucleophilic aromatic substitutions (S Ar) are amongst the most widely used processes in the pharmaceutical and agrochemical industries , allowing convergent assembly of complex molecules through C-C and C-X (X = O, N, S) bond formation. S Ar reactions are typically carried out using forcing conditi...

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Veröffentlicht in:	Nature (London) 2025-01
Hauptverfasser:	Lister, Thomas M, Roberts, George W, Hossack, Euan J, Zhao, Fei, Burke, Ashleigh J, Johannissen, Linus O, Hardy, Florence J, Millman, Alexander A V, Leys, David, Larrosa, Igor, Green, Anthony P
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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