Characterizing the microstructural transition at the gray matter-white matter interface: Implementation and demonstration of age-associated differences

•Analysis characterizes gray matter-white matter interface (GWI).•Slope of DTI/NODDI parameters demonstrates sharp GWI transition.•GWI slope magnitude decreases from age 18–91.•GWI slope can assess pathological effects on juxtacortical microstructure. The cortical gray matter-white matter interface...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2025-02, Vol.306, p.121019, Article 121019
Hauptverfasser:	Song, Joan Y, Fleysher, Roman, Ye, Kenny, Kim, Mimi, Zimmerman, Molly E, Lipton, Richard B, Lipton, Michael L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Aging Aging - pathology Aging - physiology Alzheimer's disease Anisotropy Brain Brain - anatomy & histology Brain - diagnostic imaging Contraindications Cross-Sectional Studies Diffusion Magnetic Resonance Imaging - methods Diffusion MRI Diffusion Tensor Imaging - methods DTI Einstein, Albert (1879-1955) Female GM-WM Gray Matter - diagnostic imaging Gray matter- white matter interface Humans Interface Interfaces Life span Magnetic resonance imaging Male Middle Aged Neurodegeneration Neuroimaging Slope Statistical analysis Substantia alba Substantia grisea Tissues White Matter - diagnostic imaging Young Adult
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