Factors Associated with Clinically Significant Extrinsic Compression on Gastroduodenal Endoscopy
Although clinicians frequently encounter incidentally detected gastroduodenal extrinsic compressive lesions (GDECLs) on upper gastrointestinal endoscopy (UGE), the optimal management approach for GDECLs has not been fully established. This study aimed to stratify and identify important factors assoc...
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creator | Yoon, Jin Young Bae, Jin Kyung Park, Su Bee Park, Jae Jun Jeon, Jung Won Cha, Jae Myung Shin, Sung Kwan |
description | Although clinicians frequently encounter incidentally detected gastroduodenal extrinsic compressive lesions (GDECLs) on upper gastrointestinal endoscopy (UGE), the optimal management approach for GDECLs has not been fully established. This study aimed to stratify and identify important factors associated with clinically significant GDECLs that require regular follow-up or further treatment.
Between June 2007 and December 2015, a total of 73 patients with suspected GDECLs on UGE at Kyung Hee University Hospital at Gangdong were identified and studied retrospectively. After the final diagnosis, patients were divided into the following two groups: clinically significant GDECLs, which requires regular follow-up or further treatment, and clinically non-significant GDECLs.
Among 73 GDECLs, 23 (31.5%) lesions were classified as clinically significant GDECLs and 50 (68.5%) as clinically non-significant GDECLs. In multivariate analysis, clinical and endoscopic parameters that were independently associated with clinically significant GDECLs included older age (≥ 60 years), large size (≥ 4 cm) of extrinsic compression, previous history of intra-abdominal malignancy, and symptoms of abdominal distension (all p |
doi_str_mv | 10.1007/s10620-024-08838-3 |
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Between June 2007 and December 2015, a total of 73 patients with suspected GDECLs on UGE at Kyung Hee University Hospital at Gangdong were identified and studied retrospectively. After the final diagnosis, patients were divided into the following two groups: clinically significant GDECLs, which requires regular follow-up or further treatment, and clinically non-significant GDECLs.
Among 73 GDECLs, 23 (31.5%) lesions were classified as clinically significant GDECLs and 50 (68.5%) as clinically non-significant GDECLs. In multivariate analysis, clinical and endoscopic parameters that were independently associated with clinically significant GDECLs included older age (≥ 60 years), large size (≥ 4 cm) of extrinsic compression, previous history of intra-abdominal malignancy, and symptoms of abdominal distension (all p < 0.05).
Several clinical and endoscopic parameters showed significant association with the identification of clinically significant GDECLs on endoscopy. These predictive factors might be useful in determining whether to perform further diagnostic work-up in patients with GDECLs.</description><identifier>ISSN: 0163-2116</identifier><identifier>ISSN: 1573-2568</identifier><identifier>EISSN: 1573-2568</identifier><identifier>DOI: 10.1007/s10620-024-08838-3</identifier><identifier>PMID: 39806085</identifier><language>eng</language><publisher>United States</publisher><ispartof>Digestive diseases and sciences, 2025-01</ispartof><rights>2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c184t-2e8be3d9795f7ae6a02f30a610e610ce7caf84e8e2977be8c30bb4112b473db53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39806085$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yoon, Jin Young</creatorcontrib><creatorcontrib>Bae, Jin Kyung</creatorcontrib><creatorcontrib>Park, Su Bee</creatorcontrib><creatorcontrib>Park, Jae Jun</creatorcontrib><creatorcontrib>Jeon, Jung Won</creatorcontrib><creatorcontrib>Cha, Jae Myung</creatorcontrib><creatorcontrib>Shin, Sung Kwan</creatorcontrib><title>Factors Associated with Clinically Significant Extrinsic Compression on Gastroduodenal Endoscopy</title><title>Digestive diseases and sciences</title><addtitle>Dig Dis Sci</addtitle><description>Although clinicians frequently encounter incidentally detected gastroduodenal extrinsic compressive lesions (GDECLs) on upper gastrointestinal endoscopy (UGE), the optimal management approach for GDECLs has not been fully established. This study aimed to stratify and identify important factors associated with clinically significant GDECLs that require regular follow-up or further treatment.
Between June 2007 and December 2015, a total of 73 patients with suspected GDECLs on UGE at Kyung Hee University Hospital at Gangdong were identified and studied retrospectively. After the final diagnosis, patients were divided into the following two groups: clinically significant GDECLs, which requires regular follow-up or further treatment, and clinically non-significant GDECLs.
Among 73 GDECLs, 23 (31.5%) lesions were classified as clinically significant GDECLs and 50 (68.5%) as clinically non-significant GDECLs. In multivariate analysis, clinical and endoscopic parameters that were independently associated with clinically significant GDECLs included older age (≥ 60 years), large size (≥ 4 cm) of extrinsic compression, previous history of intra-abdominal malignancy, and symptoms of abdominal distension (all p < 0.05).
Several clinical and endoscopic parameters showed significant association with the identification of clinically significant GDECLs on endoscopy. These predictive factors might be useful in determining whether to perform further diagnostic work-up in patients with GDECLs.</description><issn>0163-2116</issn><issn>1573-2568</issn><issn>1573-2568</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><recordid>eNo9kMFOwzAQRC0EoqXwAxxQjlwC6ziJnWMVtQWpEgfgbBxnA0ZpHLypoH9PoAVpVzsrzczhMXbJ4YYDyFvikCcQQ5LGoJRQsThiU55JESdZro7ZFHg-as7zCTsjegeAQvL8lE1EoSAHlU3Zy9LYwQeK5kTeOjNgHX264S0qW9c5a9p2Fz26184149MN0eJrCK4jZ6PSb_qARM530TgrQ0Pw9dbX2Jk2WnS1J-v73Tk7aUxLeHG4M_a8XDyVd_H6YXVfztex5Sod4gRVhaIuZJE10mBuIGkEmJwDjmtRWtOoFBUmhZQVKiugqlLOkyqVoq4yMWPX-94--I8t0qA3jiy2renQb0kLnmUiKwTI0ZrsrTZ4ooCN7oPbmLDTHPQPWb0nq0ey-pesFmPo6tC_rTZY_0f-UIpvaw51yA</recordid><startdate>20250113</startdate><enddate>20250113</enddate><creator>Yoon, Jin Young</creator><creator>Bae, Jin Kyung</creator><creator>Park, Su Bee</creator><creator>Park, Jae Jun</creator><creator>Jeon, Jung Won</creator><creator>Cha, Jae Myung</creator><creator>Shin, Sung Kwan</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20250113</creationdate><title>Factors Associated with Clinically Significant Extrinsic Compression on Gastroduodenal Endoscopy</title><author>Yoon, Jin Young ; Bae, Jin Kyung ; Park, Su Bee ; Park, Jae Jun ; Jeon, Jung Won ; Cha, Jae Myung ; Shin, Sung Kwan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c184t-2e8be3d9795f7ae6a02f30a610e610ce7caf84e8e2977be8c30bb4112b473db53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoon, Jin Young</creatorcontrib><creatorcontrib>Bae, Jin Kyung</creatorcontrib><creatorcontrib>Park, Su Bee</creatorcontrib><creatorcontrib>Park, Jae Jun</creatorcontrib><creatorcontrib>Jeon, Jung Won</creatorcontrib><creatorcontrib>Cha, Jae Myung</creatorcontrib><creatorcontrib>Shin, Sung Kwan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Digestive diseases and sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoon, Jin Young</au><au>Bae, Jin Kyung</au><au>Park, Su Bee</au><au>Park, Jae Jun</au><au>Jeon, Jung Won</au><au>Cha, Jae Myung</au><au>Shin, Sung Kwan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Associated with Clinically Significant Extrinsic Compression on Gastroduodenal Endoscopy</atitle><jtitle>Digestive diseases and sciences</jtitle><addtitle>Dig Dis Sci</addtitle><date>2025-01-13</date><risdate>2025</risdate><issn>0163-2116</issn><issn>1573-2568</issn><eissn>1573-2568</eissn><abstract>Although clinicians frequently encounter incidentally detected gastroduodenal extrinsic compressive lesions (GDECLs) on upper gastrointestinal endoscopy (UGE), the optimal management approach for GDECLs has not been fully established. This study aimed to stratify and identify important factors associated with clinically significant GDECLs that require regular follow-up or further treatment.
Between June 2007 and December 2015, a total of 73 patients with suspected GDECLs on UGE at Kyung Hee University Hospital at Gangdong were identified and studied retrospectively. After the final diagnosis, patients were divided into the following two groups: clinically significant GDECLs, which requires regular follow-up or further treatment, and clinically non-significant GDECLs.
Among 73 GDECLs, 23 (31.5%) lesions were classified as clinically significant GDECLs and 50 (68.5%) as clinically non-significant GDECLs. In multivariate analysis, clinical and endoscopic parameters that were independently associated with clinically significant GDECLs included older age (≥ 60 years), large size (≥ 4 cm) of extrinsic compression, previous history of intra-abdominal malignancy, and symptoms of abdominal distension (all p < 0.05).
Several clinical and endoscopic parameters showed significant association with the identification of clinically significant GDECLs on endoscopy. These predictive factors might be useful in determining whether to perform further diagnostic work-up in patients with GDECLs.</abstract><cop>United States</cop><pmid>39806085</pmid><doi>10.1007/s10620-024-08838-3</doi></addata></record> |
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title | Factors Associated with Clinically Significant Extrinsic Compression on Gastroduodenal Endoscopy |
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