M3-DPPE Liposomal Nanoparticles Encapsulating CLEC12A Enhance CD206-Mediated Endocytosis and Efficacy in the Collagen-Induced Arthritis Model

This study aimed to investigate the efficacy of M3-DPPE liposomal nanoparticles encapsulated with mRNA encoding cytokines (M3-mRNAs) in targeting macrophages for the treatment of inflammation-induced joint injury. , M3-mRNAs were administered to peritoneal exudate macrophages (PEMs), and the uptake...

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Veröffentlicht in:ACS applied bio materials 2025-01
Hauptverfasser: Luo, Shulin, Cai, Junfeng, Yin, Feng, Lu, Laiya, Liu, Zheng, Wang, Yunxia, Fu, Xiaocong, Ding, Shuangfeng, Kojima, Naoya, Ma, Min
Format: Artikel
Sprache:eng
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