Spatially Quantitative Imaging of Enzyme Activity in a Living Cell

Enzyme activity plays a key role in cell heterogeneity. Its spatially quantitative imaging in a living cell not only directly displays but also helps people to understand cell heterogeneity. Current methods are hard to achieve due to the short intracellular retention or lack of internal reference of...

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Veröffentlicht in:	Journal of the American Chemical Society 2024-12, Vol.146 (50), p.34870-34877
Hauptverfasser:	Wang, Rui, Zhou, Lei, Yang, Yueyan, Zhao, Furong, Sun, Xianbao, Liu, Xiaoyang, Zou, Zhen, Liang, Gaolin
Format:	Artikel
Sprache:	eng
Schlagworte:	cathepsin B Cathepsin B - metabolism Click Chemistry detection limit enzyme activity Humans people Raman spectroscopy Spectrum Analysis, Raman - methods
Online-Zugang:	Volltext
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