Antigen-independent single-cell circulating tumor cell detection using deep-learning-assisted biolasers

Circulating tumor cells (CTCs) in the bloodstream are important biomarkers for clinical prognosis of cancers. Current CTC identification methods are based on immuno-labeling, which depends on the differential expression of specific antigens between the cancer cells and white blood cells. Here we pre...

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Veröffentlicht in:	Biosensors & bioelectronics 2025-03, Vol.271, p.116984, Article 116984
Hauptverfasser:	Wu, Weishu, Zhang, Yu, Tan, Xiaotian, Chen, Yuru, Cao, Yuhang, Sahai, Vaibhav, Peterson, Nicole, Goo, Laura, Fry, Stacy, Kathawate, Varun, Merrill, Nathan, Qin, Angel, Merajver, Sofia D., Nagrath, Sunitha, Fan, Xudong
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarkers biosensors blood blood flow cell lines fluorescent antibody technique gene expression regulation lung neoplasms neoplasm cells pancreatic neoplasms patients prognosis
Online-Zugang:	Volltext
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