In Vitro Nicotine Exposure Induces microRNA-124 and Suppresses STAT3 Expression through the Alpha-7 Subtype of Nicotinic Acetylcholine Receptors in the SW-480 Cell Line

Nicotine is an alkaloid compound commonly found in tobacco smoke. This compound, as an agonist of nicotinic acetylcholine receptors (nAChRs), binds to these receptors and induces many downstream intracellular signaling pathways. Numerous studies have shown that nicotine leads to changes in the expre...

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Veröffentlicht in:	Biology bulletin of the Russian Academy of Sciences 2024-12, Vol.51 (Suppl 1), p.S23-S32
Hauptverfasser:	Khalil Hajiasgharzadeh, Baradaran, Behzad, Dastmalchi, Narges, Farsi, Nasim Rahimi, Hashemzadeh, Bahram, Doustvandi, Mohammad Amin, Khiabani, Nadia Allahyarzadeh, Nemati, Homeira Hatami, Khojasteh, Seyed Mahdi Banan
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Acetylcholine receptors (nicotinic) agonists Biochemistry Biomedical and Life Sciences bulls Cell Biology cell lines Colon cancer colorectal neoplasms Ecology Electroporation Gene expression Intracellular signalling Life Sciences microRNA MicroRNAs miRNA Molecular modelling neoplasm cells Nicotine Post-transcription quantitative polymerase chain reaction siRNA smoke Stat3 protein therapeutics tobacco Transfection Tumor cell lines Zoology
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