Precise photothermal treatment of bacterial infection mediated by charge-switchable nanoplatform with acylsulfonamide betaine surface

Photothermal therapy (PTT) offers a promising approach for the treatment of drug-resistant bacterial-infected wounds, yet it requires precise targeting of thermal damage to bacteria rather than healthy tissues. Herein, ultrasmall CuS NPs modified with polyzwitterion containing acylsulfonamide betain...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2025-01, Vol.245, p.114362, Article 114362
Hauptverfasser:	Sun, Wenyuan, Hu, Shumin, Lu, Binzhong, Bao, Yu, Guo, Mengyao, Yang, Yingying, Cheng, Qiuli, Zhang, Leitao, Wu, Wenlan, Li, Junbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology bacterial infections Bacterial Infections - drug therapy Bacterial Infections - therapy betaine Betaine - chemistry Betaine - pharmacology Charge reversal Copper - chemistry Copper - pharmacology death drug resistance electrostatic interactions Escherichia coli - drug effects irradiation Mice Microbial Sensitivity Tests Nanoparticles - chemistry Particle Size pH response Photothermal Therapy photothermotherapy Staphylococcus aureus - drug effects Sulfonamides - chemistry Sulfonamides - pharmacology Surface Properties Targeted photothermal therapy Wound healing Zwitterionic polymer zwitterions
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