Novel Pseudo-Two-Dimensional 19F NMR Spectroscopy for Rapid Simultaneous Detection of Amines in Complex Mixture
Rapid detection of amines in complex mixtures presents a significant challenge. Here, we introduce a novel nuclear magnetic resonance (NMR) method for amine detection utilizing a probe with two fluorine atoms in distinct chemical environments. Upon interaction with an amine, the probe generates two...
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| Veröffentlicht in: | Analytical chemistry (Washington) 2024-10, Vol.96 (42), p.16818-16824 |
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| creator | Wu, Xijian Tong, Xin Huang, Biling Huang, Shaohua |
| description | Rapid detection of amines in complex mixtures presents a significant challenge. Here, we introduce a novel nuclear magnetic resonance (NMR) method for amine detection utilizing a probe with two fluorine atoms in distinct chemical environments. Upon interaction with an amine, the probe generates two atomic resonance peaks, which are used to create coordinates, revealing fluorine chemical shifts on the 19F NMR spectroscopy. This innovative approach allows for the clear distinction of amine signals in a two-dimensional plane. This method has been effectively employed in analyzing amines in pharmaceuticals and amino acids in Ophiopogon japonicus and dry white wine, providing a robust and general approach for amine analysis. |
| doi_str_mv | 10.1021/acs.analchem.4c03521 |
| format | Article |
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This method has been effectively employed in analyzing amines in pharmaceuticals and amino acids in Ophiopogon japonicus and dry white wine, providing a robust and general approach for amine analysis.</description><subject>Amines</subject><subject>Amino acids</subject><subject>analytical chemistry</subject><subject>drugs</subject><subject>Fluorine</subject><subject>Magnetic resonance spectroscopy</subject><subject>Medical innovations</subject><subject>Mixtures</subject><subject>NMR</subject><subject>NMR spectroscopy</subject><subject>Nuclear magnetic resonance</subject><subject>nuclear magnetic resonance spectroscopy</subject><subject>Ophiopogon japonicus</subject><subject>rapid methods</subject><subject>Spectroscopic analysis</subject><subject>Spectroscopy</subject><subject>Two dimensional analysis</subject><subject>white wines</subject><issn>0003-2700</issn><issn>1520-6882</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqNkVFLwzAQx4MoOKffwIeAL750XpI2aR_H5lTYpmzzuaRpgh1tU5tW57c3YxPBJ5-OO37357gfQtcERgQouZPKjWQtS_Wmq1GogEWUnKABiSgEPI7pKRoAAAuoADhHF85tAQgBwgfILu2HLvGL031ug82nDaZFpWtXWJ-HSTLDy8UKrxututY6ZZsvbGyLV7Ipcrwuqr7sZK1t7_BUdx7ye9gaPK6KWjtc1Hhiq6bUO7wodl3f6kt0ZmTp9NWxDtHr7H4zeQzmzw9Pk_E8kJRCFyRSC2riPM98L4FJYXjC4oQLAzLmjJAwi_IoBsi54kYKLkIZUpVkRvIsC9kQ3R5ym9a-99p1aVU4pcvycG3KSBQSQRMh_oGSCBIRssSjN3_Qre1b_6k9RYFHEIXgKThQ3ssvQCDdy0r3wx9Z6VEW-wZOaIpE</recordid><startdate>20241022</startdate><enddate>20241022</enddate><creator>Wu, Xijian</creator><creator>Tong, Xin</creator><creator>Huang, Biling</creator><creator>Huang, Shaohua</creator><general>American Chemical Society</general><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7U5</scope><scope>7U7</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><orcidid>https://orcid.org/0000-0003-2407-949X</orcidid></search><sort><creationdate>20241022</creationdate><title>Novel Pseudo-Two-Dimensional 19F NMR Spectroscopy for Rapid Simultaneous Detection of Amines in Complex Mixture</title><author>Wu, Xijian ; Tong, Xin ; Huang, Biling ; Huang, Shaohua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a220t-9ae72f8ddba22a03a7f6938967f0a863114b5d5800d6c6fa7674a42c9bfa6bb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Amines</topic><topic>Amino acids</topic><topic>analytical chemistry</topic><topic>drugs</topic><topic>Fluorine</topic><topic>Magnetic resonance spectroscopy</topic><topic>Medical innovations</topic><topic>Mixtures</topic><topic>NMR</topic><topic>NMR spectroscopy</topic><topic>Nuclear magnetic resonance</topic><topic>nuclear magnetic resonance spectroscopy</topic><topic>Ophiopogon japonicus</topic><topic>rapid methods</topic><topic>Spectroscopic analysis</topic><topic>Spectroscopy</topic><topic>Two dimensional analysis</topic><topic>white wines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Xijian</creatorcontrib><creatorcontrib>Tong, Xin</creatorcontrib><creatorcontrib>Huang, Biling</creatorcontrib><creatorcontrib>Huang, Shaohua</creatorcontrib><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Analytical chemistry (Washington)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Xijian</au><au>Tong, Xin</au><au>Huang, Biling</au><au>Huang, Shaohua</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel Pseudo-Two-Dimensional 19F NMR Spectroscopy for Rapid Simultaneous Detection of Amines in Complex Mixture</atitle><jtitle>Analytical chemistry (Washington)</jtitle><addtitle>Anal. Chem</addtitle><date>2024-10-22</date><risdate>2024</risdate><volume>96</volume><issue>42</issue><spage>16818</spage><epage>16824</epage><pages>16818-16824</pages><issn>0003-2700</issn><issn>1520-6882</issn><eissn>1520-6882</eissn><abstract>Rapid detection of amines in complex mixtures presents a significant challenge. Here, we introduce a novel nuclear magnetic resonance (NMR) method for amine detection utilizing a probe with two fluorine atoms in distinct chemical environments. Upon interaction with an amine, the probe generates two atomic resonance peaks, which are used to create coordinates, revealing fluorine chemical shifts on the 19F NMR spectroscopy. This innovative approach allows for the clear distinction of amine signals in a two-dimensional plane. This method has been effectively employed in analyzing amines in pharmaceuticals and amino acids in Ophiopogon japonicus and dry white wine, providing a robust and general approach for amine analysis.</abstract><cop>Washington</cop><pub>American Chemical Society</pub><doi>10.1021/acs.analchem.4c03521</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-2407-949X</orcidid></addata></record> |
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| source | ACS Publications |
| subjects | Amines Amino acids analytical chemistry drugs Fluorine Magnetic resonance spectroscopy Medical innovations Mixtures NMR NMR spectroscopy Nuclear magnetic resonance nuclear magnetic resonance spectroscopy Ophiopogon japonicus rapid methods Spectroscopic analysis Spectroscopy Two dimensional analysis white wines |
| title | Novel Pseudo-Two-Dimensional 19F NMR Spectroscopy for Rapid Simultaneous Detection of Amines in Complex Mixture |
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