Novel Ratiometric Surface-Enhanced Raman Scattering (SERS) Biosensor for Ultrasensitive Quantitative Monitoring of Human Carboxylesterase‑1 in Hepatocellular Carcinoma Cells Using Ag–Au Nanoflowers as SERS Substrate

In this study, we developed ratiometric surface-enhanced Raman scattering (SERS) biosensors using Ag–Au alloy nanoflowers as SERS substrates, molecules having amide bonds and alkyne groups (Tag A) as Raman reporters, and sodium thiocyanate as an internal standard molecule (Tag B) for the sensitive d...

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