A potential role of human esophageal cancer-related gene-4 in cardiovascular homeostasis

Human esophageal cancer related gene-4 (ECRG-4) encodes a 148-aminoacid pre-pro-peptide that can be processed tissue-dependently into multiple small peptides possessing multiple functions distinct from, similar to, or opposite to the tumor suppressor function of the full-length Ecrg4. Ecrg-4 is cova...

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Veröffentlicht in:	Gene 2024-02, Vol.894, p.147977-147977, Article 147977
Hauptverfasser:	Wang, Chaoying, He, Jianghui, Chen, Chunyue, Luo, Wenjun, Dang, Xitong, Mao, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis atherosclerosis atrial fibrillation cardiomyopathy cardiotoxicity Cardiovascular System chemical bonding Endothelial Cells - pathology epithelium esophageal neoplasms Esophageal Neoplasms - genetics Esophageal Neoplasms - pathology heart homeostasis Humans inflammation innate immunity leukocytes nerve endings Oncogenes pathogenesis peptides signal peptide smooth muscle therapeutics tumor suppressor genes
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