Neutralization of Centruroides tecomanus scorpion venom by the use of two human recombinant antibody fragments

The first toxic component identified against mammals in the venom from Centruroides tecomanus scorpion from Colima, Mexico was Ct1a toxin, which was neutralized by human single chain variable fragment (scFv) RAS27. Venom characterization from these scorpions collected on the Pacific coast of Colima,...

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Veröffentlicht in:	Molecular immunology 2023-12, Vol.164, p.79-87
Hauptverfasser:	Valencia-Martínez, Hugo, Riaño-Umbarila, Lidia, Olamendi-Portugal, Timoteo, Romero-Moreno, José Alberto, Possani, Lourival D, Becerril, Baltazar
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid sequences Animals Centruroides coasts Humans Mammals Mexico neutralization recombinant antibodies Recombinant Proteins - chemistry Scorpion Venoms Scorpions Single-Chain Antibodies surface plasmon resonance toxicity toxins
Online-Zugang:	Volltext
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