Mechanism of PWAR6 regulating cisplatin drug sensitivity in non-small cell lung cancer through miR-577/PHACTR1

lncRNA Prader Willi/Angelman Region RNA 6 (PWAR6) is considered to play a protective lncRNA in glioma, but, the role of PWAR6 in the occurrence and cisplatin resistance of non-small cell lung cancer (NSCLC) is elusive. In the study, we aimed to assess the role of PWAR6 in the cisplatin resistance of...

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Veröffentlicht in:	Gene 2024-01, Vol.893, p.147954-147954, Article 147954
Hauptverfasser:	Tang, Wenjun, Luo, Jingru, Lin, Shu, Xu, Junnv, Yan, Qixing
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use apoptosis bioluminescence assay Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Cell Line, Tumor Cell Proliferation cell viability cisplatin Cisplatin - pharmacology Cisplatin - therapeutic use Drug Resistance, Neoplasm - genetics genes glioma Humans lung neoplasms Lung Neoplasms - drug therapy Lung Neoplasms - genetics Lung Neoplasms - metabolism microRNA MicroRNAs - metabolism RNA, Long Noncoding - genetics RNA, Small Interfering - therapeutic use
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