Green Light Activated Dual-Action Pt(IV) Prodrug with Enhanced PDT Activity

Light induced release of cisplatin from Pt(IV) prodrugs is a promising tool for precise spatiotemporal control over the antiproliferative activity of Pt-based chemotherapeutic drugs. A combination of light-controlled chemotherapy (PACT) and photodynamic therapy (PDT) in one molecule has the potentia...

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Veröffentlicht in:ChemMedChem 2025-01, p.e202400786
Hauptverfasser: Spector, Daniil, Bykusov, Vladislav, Isaeva, Yulia, Akasov, Roman, Zharova, Anastasia, Rodin, Igor, Vokuev, Mikhail, Grishin, Yuri, Nikitina, Vita, Martynov, Alexander, Kuzmin, Vladimir, Beloglazkina, Elena, Krasnovskaya, Olga
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Sprache:eng
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