Oncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors

Oncolytic viruses (OV) expressing bispecific T-cell engagers (BiTEs) are promising tools for tumor immunotherapy but the range of target tumors is limited. To facilitate effective T-cell stimulation with broad-range applicability, we established membrane-associated T-cell engagers (MATEs) harboring...

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Veröffentlicht in:	EMBO molecular medicine 2025-01
Hauptverfasser:	Peter, Malin, Mundt, Bettina, Menze, Arne, Woller, Norman, Volk, Valery, Ernst, Amanda M, Öhler, Leon A, Talbot, Steven R, Wedemeyer, Heiner, Falk, Christine, Feuerhake, Friedrich, Wirth, Thomas C, Kühnel, Florian
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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