Serum O-glycosylated HBsAg levels correlate with HBV RNA in HBeAg positive CHB patients during antiviral therapy

Recent evidence has indicated that the O-glycosylated PreS2 domain of the middle HBsAg is a distinguishing characteristic that allows the identification of HBsAg of HBV Dane particles and SVPs. This study's objective was to assess the changes in serum O-glycosylated HBsAg levels in CHB patients...

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Veröffentlicht in:	Antiviral research 2025-02, Vol.234, p.106077, Article 106077
Hauptverfasser:	Yao, Bilian, Xu, Qi, Yamada, Yousuke, Angata, Kiyohiko, Zhang, Yan, Narimatsu, Hisashi, Yu, Demin, Zhang, Xinxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - therapeutic use Biomarkers - blood DNA, Viral - blood Female Genotype Glycosylation HBV RNA Hepatitis B e Antigens - blood Hepatitis B Surface Antigens - blood Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B virusB surface antigen Hepatitis B, Chronic - blood Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Humans Interferon-alpha - therapeutic use Male Middle Aged O-glycosylated HBsAg Retrospective Studies RNA, Viral - blood Young Adult
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