Offspring NAFLD liver phospholipid profiles are differentially programmed by maternal high-fat diet and maternal one carbon supplement

Little is known if and how maternal diet affects the liver phospholipid profiles that contribute to non-alcoholic fatty liver disease (NAFLD) development in offspring. We examined NAFLD phenotypes in male offspring mice of either maternal normal-fat diet (NF group), maternal high-fat diet (HF group)...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2023-01, Vol.111, p.109187-109187, Article 109187
Hauptverfasser:	Peng, Hui, Li, Jiangyuan, Xu, Huiting, Wang, Xian, He, Leya, McCauley, Naomi, Zhang, Ke K., Xie, Linglin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals bisulfites carbon Carbon - metabolism Diet, High-Fat - adverse effects DNA methylation fatty liver Female gene expression genome high fat diet Humans lactation liver Liver - metabolism Male males maternal nutrition Maternal Nutritional Physiological Phenomena metabolism methionine Mice NAFLD Non-alcoholic Fatty Liver Disease - metabolism One-Carbon Supplement Phospholipid profile phospholipids Phospholipids - metabolism pregnancy Prenatal Exposure Delayed Effects - metabolism progeny WGBS
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