Metal-Free Synthesis of 2‑(per)Fluoroalkyl-3-nitro Indoles via Intramolecular Cyclization of Amides

A metal-free intramolecular cyclization of N-acyl amides for the synthesis of 3-nitro-2-(per)­fluoroalkyl indoles is reported. Good functional group tolerance and a broad range of substrates are the features of this approach. The developed method is easy to operate and is suitable for the preparatio...

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Veröffentlicht in:	Journal of organic chemistry 2024-10, Vol.89 (19), p.14028-14037
Hauptverfasser:	Sterligov, Grigorii K., Rasskazova, Maria A., Drokin, Egor A., Isaeva, Dilshodakhon K., Ageshina, Alexandra A., Rzhevskiy, Sergey A., Shurupova, Olga V., Topchiy, Maxim A., Minaeva, Lidiya I., Asachenko, Andrey F.
Format:	Artikel
Sprache:	eng
Schlagworte:	amides cyclization reactions indoles organic chemistry
Online-Zugang:	Volltext
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