Soluble dietary fiber and cellulose from Saccharina japonica by-product ameliorate Loperamide-induced constipation via modulating enteric neurotransmitters, short-chain fatty acids and gut microbiota

The effects of soluble dietary fiber (SDF) and cellulose (IDF) from Saccharina japonica by-product and their differences in improving constipation were further clarified in the present study. We demonstrated that SDF was mainly made up of d-mannuronic acid and d-mannose while IDF consisted of d-gluc...

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Veröffentlicht in:	International journal of biological macromolecules 2023-01, Vol.226, p.1319-1331
Hauptverfasser:	Cao, Junhan, Wang, Kai, Li, Nianxu, Zhang, Liping, Qin, Ling, He, Yingying, Wang, Jingfeng, Qu, Changfeng, Miao, Jinlai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antioxidants biosynthesis byproducts Cellulose Cellulose - pharmacology Constipation Constipation - chemically induced Constipation - drug therapy dietary fiber Dietary Fiber - metabolism Dietary Fiber - pharmacology dietary supplements Fatty Acids, Volatile - metabolism Gastrointestinal Microbiome gastrointestinal transit glucose glucuronic acid Gut microbiota histology homeostasis Humans IDF intestinal microorganisms intestines Lachnospiraceae Loperamide mannose Mice Neurotransmitter Agents neurotransmitters occludins Phaeophyceae - metabolism Saccharina japonica SCFAs SDF water holding capacity
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