The antibacterial mechanism of (−)‐epigallocatechin‐3‐gallate (EGCG) against Campylobacter jejuni through transcriptome profiling

(−)‐Epigallocatechin‐3‐gallate (EGCG) has been shown antibacterial activity against Campylobacter jejuni; however, the relevant antibacterial mechanism is unknown. In this study, phenotypic experiments and RNA sequencing were used to explore the antibacterial mechanism. The minimum inhibitory concen...

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Veröffentlicht in:	Journal of food science 2024-04, Vol.89 (4), p.2384-2396
Hauptverfasser:	Lin, Yilin, Liang, Siwei, Zhang, Yehui, Yu, Yigang
Format:	Artikel
Sprache:	eng
Schlagworte:	(‐)‐Epigallocatechin‐3‐gallate Antibacterial activity Antibacterial agents antibacterial mechanism antibacterial properties antibiotics bacterial motility Biosynthesis Campylobacter Campylobacter jejuni Cell membranes Chelation Cytology electron microscopy Emission analysis Epigallocatechin gallate Field emission microscopy Flagella Flagellin flagellum Fluorescence fluorescence microscopy Food Food industry Food safety Gene sequencing genes human health Iron Iron deficiency Microscopy Minimum inhibitory concentration Motility Nutrient deficiency Oxidative stress phenotype Reactive oxygen species Ribonucleic acid RNA RNA‐sequencing Scanning electron microscopy sequence analysis Thioredoxin thioredoxins transcriptome Transcriptomes Virulence
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