Assessing nanotoxicity of food-relevant particles: A comparative analysis of cellular responses in cell monolayers versus 3D gut epithelial cultures

Engineered nanoparticles (NPs) are extensively used in the food industry, yet safety concerns remain. The lack of validated methodologies is a bottleneck towards resolving this uncertainty. Hence, the current study aims to compare two cell models by examining the toxicological impacts of two food-re...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Food and chemical toxicology 2024-11, Vol.193, p.115055, Article 115055
Hauptverfasser:	Gautam, Archana, Lim, Hui Kheng, Li, Jasmine Jia’En, Hughes, Christopher Owen, Yeo, Calvin Wee Sing, Rakshit, Moumita, Leavesley, David Ian, Lim, Michelle Jing Sin, Tan, Joseph Choon Wee, Tan, Li Yi, Chan, Joanne Sheot Harn, Smith, Benjamin Paul Chapman, Ng, Kee Woei
Format:	Artikel
Sprache:	eng
Schlagworte:	3D models autophagy Caco-2 Cells Cell Culture Techniques, Three Dimensional - methods Cell Survival - drug effects cytotoxicity Epithelial Cells - drug effects epithelium food industry Genotoxicity Humans Intestinal Mucosa - cytology Intestinal Mucosa - drug effects Intestine Intestine, Small - cytology Intestine, Small - drug effects intestines Metal Nanoparticles - toxicity Nanoparticles Nanotoxicology Silicon Dioxide - toxicity Silver - toxicity toxicity testing transmission electron microscopy uncertainty
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!