3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans

In cancer microenvironment, aberrant glycosylation events of ECM proteins and cell surface receptors occur. We developed a protocol to generate 3D bioprinted models of colorectal cancer (CRC) crosslinking hyaluronic acid and gelatin functionalized with three signalling glycans characterized in CRC,...

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Veröffentlicht in:	Carbohydrate polymers 2023-02, Vol.302, p.120395-120395, Article 120395
Hauptverfasser:	Cadamuro, Francesca, Marongiu, Laura, Marino, Michele, Tamini, Nicolò, Nespoli, Luca, Zucchini, Nicola, Terzi, Alberta, Altamura, Davide, Gao, Zirui, Giannini, Cinzia, Bindi, Greta, Smith, Andrew, Magni, Fulvio, Bertini, Sabrina, Granucci, Francesca, Nicotra, Francesco, Russo, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	3D bioprinting azides biocompatibility Bioresponsive hydrogels Colorectal cancer models Colorectal Neoplasms crosslinking gelatin Gelatin - pharmacology Glycosignature glycosylation Humans Hyaluronic Acid hydrogels Hydrogels - pharmacology patients Polysaccharides proteome Scattering, Small Angle Tissue Engineering - methods Tissue Scaffolds Tumor Microenvironment X-Ray Diffraction
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