Garlic Extract Promotes Pancreatic Islet Neogenesis Through α‐to‐β‐Cell Transdifferentiation and Normalizes Glucose Homeostasis in Diabetic Rats

Scope Garlic extract (GE) has been shown to ameliorate hyperglycemia in diabetic rats (DRs) by increasing insulin production. However, the mechanism through which it exerts its effects remains unclear. Here, it investigates the molecular process and the origin of regenerating β‐cell in rats with str...

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Veröffentlicht in:	Molecular nutrition & food research 2024-10, Vol.68 (19), p.e2400362-n/a
Hauptverfasser:	Al‐Adsani, Amani M., Al‐Qattan, Khaled K., Barhoush, Sahar A., Abbood, Manal S., Al‐Bustan, Suzanne A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Beta cells Beta2 protein Cell differentiation Cells (biology) Diabetes Diabetes mellitus Differentiation Fibrosarcoma food research garlic garlic extract Glucose Glucose transporter glucose transporters Homeobox Homeostasis Hyperglycemia immunohistochemistry Insulin Insulin secretion islet regeneration islets of Langerhans nutrition oncogenes Pancreas Plant extracts Progenitor cells stem cells Streptozocin streptozotocin Subpopulations transcription factors Western blotting β‐cell
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