Design and functional characterization of Salmo salar TLR5 agonist peptides derived from high mobility group B1 acidic tail

Toll-like receptor 5 (TLR5) responds to the monomeric form of flagellin and induces the MyD88-depending signaling pathway, activating proinflammatory transcription factors such as NF-κB and the consequent induction of cytokines. On the other hand, HMGB1 is a highly conserved non-histone chromosomal...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Fish & shellfish immunology 2024-03, Vol.146, p.109373-109373, Article 109373
Hauptverfasser:	Vásquez-Suárez, Aleikar, Muñoz-Flores, Carolina, Ortega, Leonardo, Roa, Francisco, Castillo, Carolina, Romero, Alex, Parra, Natalie, Sandoval, Felipe, Macaya, Luis, González-Chavarría, Iván, Astuya, Allisson, Starck, María Francisca, Villegas, Milton F., Agurto, Niza, Montesino, Raquel, Sánchez, Oliberto, Valenzuela, Ariel, Toledo, Jorge R., Acosta, Jannel
Format:	Artikel
Sprache:	eng
Schlagworte:	agonists algorithms circular dichroism spectroscopy cytokines fish flagellin gene expression HMGB1 Immune response Immunostimulant immunostimulants nucleoproteins phosphorylation Piscirickettsia salmonis Salmo salar Salmonids shellfish TLR5 Toll-like receptor 5
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!