FTR33, a member of fish-specific TRIM (finTRIM) subfamily, regulates negatively type I IFN antiviral immunity in zebrafish

In mammals, the tripartite motif (TRIM) proteins have been identified as critical factors involved in various cellular processes, including antiviral immunity. In teleost fish, a subfamily of fish-specific TRIM (finTRIM, FTR) has emerged in genus- or species-specific duplication. In this study, a fi...

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Veröffentlicht in:	Developmental and comparative immunology 2023-05, Vol.142, p.104671, Article 104671
Hauptverfasser:	Huang, Lin, Zhang, Lin, Huo, Hui Jun, Hou, Jing, Niu, Meng Meng, Nie, Pin, Chen, Shan Nan
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Animals Carp sprivivirus Carps - metabolism Danio rerio finTRIM Fish Diseases FTR33 gene expression genes IFN ifnu immunity Immunity, Innate - genetics Interferon Type I - genetics interferons Interferons - metabolism Mammals melanoma mitochondria phylogeny RLR subfamily Zebrafish Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
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