An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development

Macrophages are heterogeneous and play critical roles in development and disease, but their diversity, function, and specification remain inadequately understood during human development. We generated a single-cell RNA sequencing map of the dynamics of human macrophage specification from PCW 4–26 ac...

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Veröffentlicht in:	Cell 2023-09, Vol.186 (20), p.4454-4471.e19
Hauptverfasser:	Wang, Zeshuai, Wu, Zhisheng, Wang, Hao, Feng, Ruoqing, Wang, Guanlin, Li, Muxi, Wang, Shuang-Yin, Chen, Xiaoyan, Su, Yiyi, Wang, Jun, Zhang, Weiwen, Bao, Yuzhou, Lan, Zhenwei, Song, Zhuo, Wang, Yiheng, Luo, Xianyang, Zhao, Lingyu, Hou, Anli, Tian, Shuye, Gao, Hongliang, Miao, Wenbin, Liu, Yingyu, Wang, Huilin, Yin, Cui, Ji, Zhi-Liang, Feng, Mingqian, Liu, Hongkun, Diao, Lianghui, Amit, Ido, Chen, Yun, Zeng, Yong, Ginhoux, Florent, Wu, Xueqing, Zhu, Yuanfang, Li, Hanjie
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Cell Differentiation Cell Lineage developmental immunology heart human development human immunology Humans immune cell atlas macrophage macrophages Macrophages - cytology melanocytes Microglia microglia-like cells neural crest neural crest cells neuroglia Organ Specificity perivascular macrophages prenatal development RNA scRNA-seq testes
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