Gene expression of TRPMLs and its regulation by pathogen stimulation

•The gene expression of three TRPMLs is abundant in mouse spleen, lung, and kidney tissues.•Three TRPMLs show different responses to pathogen stimuli in lung tissue and A549 cells.•The responses of three TRPMLs to pathogen stimuli that occur similarly in other tissues.•LPS exhibits a significant eff...

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Veröffentlicht in:	Gene 2023-05, Vol.864, p.147291-147291, Article 147291
Hauptverfasser:	Xia, Zhiqiang, Xie, Lixia, Li, Dongyuan, Hong, Xinyi, Qin, Chenhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals autophagy calcium dose response Gene Expression genes Homeostasis innate immunity interleukin-6 kidneys Lipopolysaccharides - metabolism Lung tissue lungs Lysosomes Mammals - genetics Mice Pathogen invasion pathogens qRT-PCR Salmonella Specific activator spleen subfamily Transient Receptor Potential Channels - genetics Transient Receptor Potential Channels - metabolism TRPML
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