Coordination regulation of enhanced performance reveals the tolerance mechanism of Chlamys farreri to azaspiracid toxicity

Azaspiracids (AZAs) are lipid biotoxins produced by the marine dinoflagellates Azadinium and Amphidoma spp. that can accumulate in shellfish and cause food poisoning in humans. However, the mechanisms underlying the tolerance of shellfish to high levels of such toxins remain poorly understood. This...

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Veröffentlicht in:	Journal of hazardous materials 2024-09, Vol.476, p.135247, Article 135247
Hauptverfasser:	Wu, Haiyan, Zhang, Qianru, Dong, Chenfan, Zheng, Guanchao, Tan, Zhijun, Gu, Haifeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphidoma Animals autophagy Azadinium azaspiracid Azaspiracids Azumapecten farreri Detoxification energy energy metabolism Energy Metabolism - drug effects Glutathione hemocytes homeostasis immune system lipids Marine Toxins - toxicity metabolites mitochondria Oxidative stress Pectinidae - drug effects Pectinidae - immunology Pectinidae - metabolism Polyether Toxins Reactive Oxygen Species - metabolism Shellfish Spiro Compounds - toxicity Tolerance toxicity toxins transcriptome Transcriptome - drug effects tricarboxylic acid cycle
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