Study of the antibacterial and cytotoxic activity of chitosan and its derivatives chemically modified with phthalic anhydride and ethylenediamine

The insertion of hydrophobic and hydrophilic chains in the chitosan molecule can improve its antibacterial activity, expanding its range of application in several areas of medical-pharmaceutical sciences. Thus, this work aimed to increase the antibacterial activity of chitosan through the modificati...

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Veröffentlicht in:	International journal of biological macromolecules 2024-04, Vol.263 (Pt 1), p.130292-130292, Article 130292
Hauptverfasser:	Sousa, Janete M., Braz, Elton M.A., Bezerra, Roosevelt D.S., Morais, Alan I.S., Vieira, Alexandre C.C., Costa, Marcilia P., Rizzo, Marcia S., Chaves, Luíse L., Barreto, Humberto M., Osajima, Josy A., Silva-Filho, Edson C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity antibacterial properties chitosan Chitosan - chemistry Cytotoxicity Escherichia coli ethylenediamines Ethylenediamines - pharmacology fibroblasts Fourier transform infrared spectroscopy Humans hydrophilicity hydrophobicity Microbial Sensitivity Tests Modified chitosan nuclear magnetic resonance spectroscopy phthalic anhydride Phthalic Anhydrides - pharmacology Spectroscopy, Fourier Transform Infrared Staphylococcus aureus tetrazolium thermogravimetry X-Ray Diffraction
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