Expression of CD44 is regulated by ELF3 in 5-FU treated colorectal cancer cells

•The expression of CD44, including some other CSC markers were all increased after 5-FU treatment of CRC cells. The stemness properties of survived CRC cells were also observed to be enhanced.•RNA-seq analysis revealed that ELF3 was increased along with CD44 after 5-FU treatment in CRC cells.•The ex...

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Veröffentlicht in:	Gene 2024-01, Vol.892, p.147896-147896, Article 147896
Hauptverfasser:	Li, Fangzhou, Qiu, Fen, Fan, Xu, Yu, Qingqing, Liu, Shuaitong, Guo, Yang, Zhu, Yunhe, Xi, Xueyan, Du, Boyu
Format:	Artikel
Sprache:	eng
Schlagworte:	5-fluorouracil bioluminescence assay CD44 Chemotherapy Colorectal cancer colorectal neoplasms drug therapy ELF3 family fluorouracil genes sequence analysis
Online-Zugang:	Volltext
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