Mass Spectrometry-Based Multiomics Identifies Metabolic Signatures of Sarcopenia in Rhesus Monkey Skeletal Muscle

Sarcopenia is a progressive disorder characterized by age-related loss of skeletal muscle mass and function. Although significant progress has been made over the years to identify the molecular determinants of sarcopenia, the precise mechanisms underlying the age-related loss of contractile function...

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Veröffentlicht in:	Journal of proteome research 2024-08, Vol.23 (8), p.2845-2856
Hauptverfasser:	Pergande, Melissa R., Osterbauer, Katie J., Buck, Kevin M., Roberts, David S., Wood, Nina N., Balasubramanian, Priya, Mann, Morgan W., Rossler, Kalina J., Diffee, Gary M., Colman, Ricki J., Anderson, Rozalyn M., Ge, Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine monophosphate adenosine triphosphate Aging - metabolism Animals beta oxidation carbohydrates Energy Metabolism fatty acids Fatty Acids - metabolism Macaca mulatta Male mass spectrometry Mass Spectrometry - methods metabolites Metabolome metabolomics Metabolomics - methods multiomics Multiomics - methods Muscle Proteins - metabolism Muscle, Skeletal - metabolism muscles proteome proteomics Proteomics - methods sarcopenia Sarcopenia - metabolism Sarcopenia - pathology skeletal muscle therapeutics
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