Methylation Levels in the 5' Region of the TBX20 Gene in the Ascending Aorta Change in Opposite Direction in Atherosclerosis and Aneurysm

We found hypomethylation of five CpG sites in the 5' region of TBX20 gene (7p14.2) in the tissues of atherosclerotic aortic plaque compared to dilated part of aorta in patients with ascending aortic aneurysm. Using GEO database, we found that the DNA methylation level in the chr7:35253926-35262...

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Veröffentlicht in:	Russian journal of genetics 2024-07, Vol.60 (7), p.977-981
Hauptverfasser:	Koroleva, Iu. A., Goncharova, I. A., Zarubin, A. A., Shipulina, S. A., Sleptsov, A. A., Panfilov, D. S., Kozlov, B. N., Nazarenko, M. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	aneurysm Animal Genetics and Genomics aorta atherosclerosis Biomedical and Life Sciences Biomedicine dissection DNA methylation epigenetics genes Human Genetics Microbial Genetics and Genomics Short Communications
Online-Zugang:	Volltext
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