Identification, characterization, and molecular docking of immunomodulatory oligopeptides from bioavailable hempseed protein hydrolysates

[Display omitted] •Hemp protein hydrolysates are bioavailable in a CACO-2 cells transwell model.•Bioavailable hydrolysates showed immunomodulatory activity.•Peptidome of hydrolysates was identified, characterized, and analyzed in silico.•Chemically synthesized peptides validated experimentally the b...

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Veröffentlicht in:	Food research international 2024-01, Vol.176, p.113712-113712, Article 113712
Hauptverfasser:	Millan-Linares, Maria C., Rivero-Pino, Fernando, Gonzalez-de la Rosa, Teresa, Villanueva, Alvaro, Montserrat-de la Paz, Sergio
Format:	Artikel
Sprache:	eng
Schlagworte:	absorption anti-inflammatory activity bioavailability Biopeptides Cannabis sativa cell culture computer simulation enzymatic hydrolysis food research gene expression Hemp human cell lines humans Immunometabolism immunomodulators Immunonutrition ingestion interleukin-10 interleukin-4 interleukin-6 monocytes oligopeptides Sustainability sustainable agriculture
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