Usefulness of a murine model of hepatic cystic echinococcosis for preclinical drug trials: Efficacy of albendazole vs albendazole nanocrystals

Cystic echinococcosis is a zoonotic infection caused by the larval stage of Echinococcus granulosus sensu lato. The disease is characterized by the long-term growth of cysts, most commonly in the liver and lungs. Although an ideal model of cystic echinococcosis should induce the development of cysts...

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Veröffentlicht in:	Acta tropica 2024-09, Vol.257, p.107285, Article 107285
Hauptverfasser:	Pensel, Patricia E, Scioscia, Nathalia P, Nieto, Nicolás, Zoppi, Jorge, Chaparro, Mauro, Paredes, Alejandro J, Albani, Clara M., Palma, Santiago D, Elissondo, María C.
Format:	Artikel
Sprache:	eng
Schlagworte:	albendazole Albendazole nanocrystals animal models Cystic echinococcosis echinococcosis Echinococcus granulosus Experimental murine model humans larvae liver nanocrystals pharmacokinetics ultrasonics zoonoses
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