Alum-tuned hyaluronic acid-based hydrogel with immune checkpoint inhibition for immunophoto therapy of cancer

Alum-crosslinked hyaluronic acid-dopamine (HD) hydrogel containing indocyanine green (ICG) with anti-programmed cell death-1 (PD-1) antibody (Ab) administration was developed for immunophoto therapy of cancer. Alum modulates the rheological characteristics of hydrogel for enabling syringe injection,...

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Veröffentlicht in:	Journal of controlled release 2023-10, Vol.362, p.1-18
Hauptverfasser:	Kim, Sungyun, Ahn, Jae-Hee, Jeong, Da In, Yang, Mingyu, Jeong, Jae-Hyeon, Choi, Yeoung Eun, Kim, Hyun Jin, Han, Youngjoo, Karmakar, Mrinmoy, Ko, Hyun-Jeong, Cho, Hyun-Jong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alum antibodies biodegradation cancer therapy Colorectal cancer fever Hydrogel hydrogels Immune checkpoint inhibition irradiation neoplasm cells neoplasms Phototherapy singlet oxygen syringes
Online-Zugang:	Volltext
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