Evaluation of the 52-week chronic toxicity of a novel phthalate-free plasticizer, Eco-DEHCH (bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate), in Han Wistar rats

Phthalate esters (PEs) are the most widely used class of plasticizers. Several PEs, however, were found to have adverse effects on the health of animals. A new phthalate-free plasticizer, Eco-DEHCH (bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate), was recently developed as an ecofriendly replacemen...

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Veröffentlicht in:	Food and chemical toxicology 2023-06, Vol.176, p.113809-113809, Article 113809
Hauptverfasser:	Lee, Ji-Young, Han, Hyo-Jeong, Ko, Soo Min, Jeong, Da Som, Kang, Jiyeon, Lee, Dong Hyun, Cha, Hwa Jun, Son, Woo-Chan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative plasticizer Animals Bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate blood serum Carboxylic Acids chronic exposure chronic toxicity class coagulation Cyclohexanes Diethylhexyl Phthalate - toxicity Drug-Related Side Effects and Adverse Reactions Eco-DEHCH Esters - chemistry Female females food consumption histopathology Humans Male males Phthalate-free plasticizer phthalates Phthalic Acids - toxicity plasticizers Plasticizers - toxicity Rats Rats, Wistar tissue weight urinalysis
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