Adipocyte-derived exosomes promote the progression of triple-negative breast cancer through circCRIM1-dependent OGA activation

Triple-negative breast cancer (TNBC) has an escalating morbidity and a dismal prognosis. Obesity has been reported to be strongly linked to adverse TNBC outcomes. Exosomes (Exos) transport RNA and proteins between cells and serve as intermediaries for cell-to-cell communication. Accumulated evidence...

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Veröffentlicht in:	Environmental research 2023-12, Vol.239, p.117266-117266, Article 117266
Hauptverfasser:	Li, Yuehua, Jiang, Baohong, Zeng, Lijun, Tang, Yuanbin, Qi, Xiaowen, Wan, Zhixing, Feng, Wenjie, Xie, Liming, He, Rongfang, Zhu, Hongbo, Wu, Yimou
Format:	Artikel
Sprache:	eng
Schlagworte:	adipocytes body fat breast neoplasms cell communication CircCRIM1 Environmental factors evolution Exosomes glycosylation hydrolases Immune infiltration metastasis morbidity neoplasm cells obesity OGA prognosis RNA Triple-negative breast cancer
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