Neuroprotective and anti-inflammatory effects of curcumin in Alzheimer's disease: Targeting neuroinflammation strategies

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-beta plaques and neurofibrillary tangles, leading to neuronal loss. Curcumin, a polyphenolic compound derived from Curcuma longa, has shown potential neuroprotective effects due to...

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Veröffentlicht in:	Phytotherapy research 2024-06, Vol.38 (6), p.3169-3189
Hauptverfasser:	Azzini, Elena, Peña-Corona, Sheila I, Hernández-Parra, Héctor, Chandran, Deepak, Saleena, Lejaniya Abdul Kalam, Sawikr, Yousef, Peluso, Ilaria, Dhumal, Sangram, Kumar, Manoj, Leyva-Gómez, Gerardo, Martorell, Miquel, Sharifi-Rad, Javad, Calina, Daniela
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer disease Alzheimer Disease - drug therapy Alzheimer's disease Animals Anti-Inflammatory Agents - pharmacology Antioxidants - pharmacology Bioavailability Biological Availability Clinical trials Curcuma - chemistry Curcuma longa Curcumin Curcumin - pharmacology Curcumin - therapeutic use cytokines Humans Inflammation Medical research Neurodegenerative diseases Neurofibrillary tangles Neuroinflammatory Diseases - drug therapy neurons Neuroprotection Neuroprotective Agents - pharmacology neuroprotective effect Pharmacokinetics phytotherapy Reactive oxygen species Scavenging System effectiveness
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