Distinct Sub- to Superdiffuse Insulin Granule Transport Behaviors in β‑Cells Are Strongly Affected by Granule Age

Intracellular transport is a complex process that is difficult to describe by a single general model for motion. Here, we study the transport of insulin containing vesicles, termed granules, in live MIN6 cells. We characterize how the observed heterogeneity is affected by different intracellular fac...

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Veröffentlicht in:	The journal of physical chemistry. B 2024-07, Vol.128 (26), p.6246-6256
Hauptverfasser:	Yi, Hannah, Gong, Daozheng, Daddysman, Matthew K., Renn, Martha, Scherer, Norbert F.
Format:	Artikel
Sprache:	eng
Schlagworte:	actin B: Biophysical and Biochemical Systems and Processes cell lines confocal microscopy CRISPR-Cas systems insulin microtubules physical chemistry physiological transport statistical analysis
Online-Zugang:	Volltext
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