Role of endoplasmic reticulum aminopeptidase-1 gene polymorphism (rs13167972) in occurrence susceptibility of ankylosing spondylitis in a sample of Iraqi male patients

Background Ankylosing spondylitis (AS) is a chronic and systemic seronegative inflammatory spondyloarthropathy, an autoimmune disease that has been associated with impaired Endoplasmic Reticulum Aminopeptidase (ERAP)-1 activity, which is involved in priming antigenic peptides. The purpose of this st...

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Veröffentlicht in:	Molecular biology reports 2024-12, Vol.51 (1), p.462-462, Article 462
Hauptverfasser:	Hassan, Sumyah Hussein, Auda, Ibtesam Ghadban, Ali, Ekhlass N., Alosami, Mohammed Hadi, Hussein, Ranya H.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Alleles Aminopeptidase aminopeptidases Animal Anatomy Animal Biochemistry Ankylosing spondylitis Arthritis Autoimmune diseases Biomedical and Life Sciences Blood group O Blood groups blood serum Body mass index C-reactive protein disease incidence Endoplasmic reticulum Erythrocyte sedimentation rate Gene polymorphism genetic polymorphism Genotyping Histology Life Sciences Magnetic resonance imaging magnetism Males Morphology Original Article overweight patients peptides Polymorphism Risk factors Spondyloarthropathy
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